Working with Windows Programs
Although Linux offers an increasingly compelling platform for the desktop, some situations arise when there is just no alternative other than an application written for Windows. This is generally the case with specific business applications, some educational tools, and many games. Luckily, there is a way you can run many of these applications on your Ubuntu desktop.
For more than fifteen years, the Wine project team members have been working to create a free way to run Windows applications on Linux. While not every application works perfectly, and some don't work at all, the number of programs that do work in Wine has dramatically increased and continues to do so. However, it is recommended that you thoroughly test the applications you want to run in Wine before you use them for important work, and if you run into trouble, try consulting help resources, use virtualization to run Windows on top of Ubuntu, or search for a different application to use.
Install the Wine package from the System Tools section of the Ubuntu Software Center or simply double-click an .exe file, and you will be prompted to install the package. You can configure Wine at System > Preferences > Wine Applications. Your C:\ Drive will appear in your Places menu for easy access, and you will be able to uninstall Wine from the Ubuntu Software Center.
Running Applications
To run an application, simply double-click on the install .exe file. Once installed, the program should appear in your menu under Applications > Wine.